Melanoma PET/CT Utilization and Case Studies

PET/CT is a noninvasive test that physicians utilize to stage the body for the presence or absence of active tumor, localize the tumor, assess the tumor response to treatment and detect recurrence in treated lesions.

PET/CT Utilization for Melanoma

  1. Preoperative staging for patients with clinically suspected lymph node involvement, or symptoms suspicious for distant metastases
  2. Preoperative staging for patients who have a high risk of systemic metastasis based on extensive locoregional tumor
  3. Preoperative staging in patients with known metastasis who may benefit from resection
  4. Postsurgical and restaging follow-up of patients at high risk for spread

Note: The sensitivity of PET/CT for detecting regional lymph node involvement is low due to micrometastatic disease which is too small to detect. Evaluation of local and regional lymph node metastases is performed by sentinel node mapping and biopsy.

Source: Atlas of Clinical Positron Emission Tomography by Sallie F. Barrington, Michael N. Maisey and Richard R. Wahl. Oxford University Press, Inc. New York, NY. Oncologic PET/CT: A primer for radiologists by Stephen Humes, MD. AuntMinnie.com

Case Studies

Title Description Author
Case 01 Restaging melanoma Dr. Todd Blodgett, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
Case 02 Restaging melanoma Dr. Todd Blodgett, University of Pittsburgh Medical Center, Pittsburgh, PA, USA