Metastatic Bone Disease PET/CT Utilization and Case Studies

Sodium fluoride F 18 (18F NaF) bone PET/CT imaging is a noninvasive test that physicians utilize to stage the body for the presence or absence of active bone tumors, localize the tumors, assess the tumors' response to treatment and detect recurrence in treated lesions.

PET/CT Utilization in Metastatic Bone Disease

  1. Identifying skeletal metastases in patients with a range of primary tumors
  2. Performing initial evaluation and staging of metastatic disease in the skeleton
  3. Localizing metastatic bone disease
  4. Characterizing benign or malignant lesions in patients at risk for bone metastases
  5. Assessing response of skeletal metastases to therapy
  6. Detecting skeletal metastases during follow-up
  7. Detecting primary tumors of the bone and identifying sites of disease
  8. Assessing response to therapy in primary bone tumors
  9. Detecting recurrent disease in primary bone tumors
Source: Grant. 2008. Skeletal PET with 18F-Fluoride: Applying New Technology to an Old Tracer JNM 2008; 49(1):68-78

Case Studies

Title Description Author
Case 01 18F NaF PET bone imaging vs. planar 99mTc MDP in a patient with breast cancer Dr. David Haseley and Dr. Gustavo Mercier, Seattle Nuclear Medicine, Seattle, WA, USA
Case 02 18F NaF bone scan in a patient with breast cancer reveals mild degenerative changes Dr. David Townsend, University of Tennessee Medical Center, Knoxville, TN, USA